A double-blind comparison of the anti-emetic effect during labour of metoclopramide and perphenazine.

نویسنده

  • J M McGarry
چکیده

The anti-emetic properties of metoclopramide were investigated by means of a doubleblind trial in normal labour in 584 women. The drug was also compared with an established anti-emetic drug, perphenazine. All patients were given pethidine as an analgesic. The incidence of vomiting after metoclopramide 10 mg or perphenazine 5 mg was significantly less than after normal saline. The incidences after perphenazine and metoclopramide were not significantly different. In the three groups studied there was no difference in the parity, length of labour, mode of delivery or Apgar score of the babies.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of the preventive effect of ketamine, paracetamol and metoclopramide on postoperative pain intensity in general anesthesia: a double-blind clinical trial

Background and Aim: Postoperative pain is one of the most common complications after eye surgeries, especially cataract. Use of analgesic drugs before surgery can be effective in decreasing the pain. The purpose of this study was to investigate preemptive effect of ketamine, paracetamol, and metoclopramide on the postoperative pain in the patients following cataract surgery with general anesthe...

متن کامل

Prophylaxis of postoperative vomiting in children undergoing tonsillectomy: a systematic review and meta-analysis.

Postoperative vomiting (POV) remains one of the commonest causes of significant morbidity after tonsillectomy in children. A variety of prophylactic anti-emetic interventions have been reported, but there has only been a limited systematic review in this patient group. A systematic search was performed by using Cochrane Controlled Trials Register, MEDLINE and EMBASE to identify double-blind, ra...

متن کامل

Anti-emetic effect of high-dose metoclopramide vs alizapride--a randomised crossover study.

A randomised double-blind crossover study was undertaken to compare the anti-emetic efficacy of alizapride against high dose metoclopramide. A total of 32 patients on cisplatin were randomised to receive either high dose metoclopramide (7 mg kg-1 day-1) or alizapride (5 mg kg-1 day-1). Anti-emetic responses in terms of control of vomiting episodes were similar in both regimens (59%). However, p...

متن کامل

Comparison of the effect of Dexamethasone - Metoclopramide combination and ondansetron in the prevention of nausea and vomiting in cesarean section under spinal Anesthesia

Introduction: Nausea and vomiting is one of the complications of spinal anesthesia in cesarean section. The aim of this study was to compare the effects of dexamethasone-metocloprmide with ondansetrone on preventing nausea and vomiting during spinal Anesthesia for cesarean section. Methods: In this study 212 pregnant women (17-45 years old) candidate for elective cesarean section with an ASA...

متن کامل

Comparing the effect of metoclopramide and promethazine on preventing nausea and vomiting after laparoscopic cholecystectomy: A double-blind clinical trial

Introduction: Nausea and vomiting are conditions that could occur after anesthesia and lead to reduced activity and surgery dissatisfaction. Therefore, according to its importance, this study was accomplished in order to compere the effect of metoclopramide and promethazine on preventing nausea and vomiting after laparoscopic cholecystectomy. Materials and Methods: This study was a double-blind...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • British journal of anaesthesia

دوره 43 6  شماره 

صفحات  -

تاریخ انتشار 1971